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Transforming the understanding
and treatment of mental illnesses.

Science Updates from 2025

A doctor filling out a form sitting across from a patient.
Developing Tools for Measuring Mental Health Outcomes

The National Institutes of Health has funded six projects to develop, test, and validate outcome-focused quality measures for mental health, which are used to understand the impact of interventions when implemented in real-world health care systems and settings.

An illustration showing a profile view of a woman’s face in a peaceful pose with her eyes closed. Overlaying the back of her head is the outline of a brain.
How the Brain Creates New Memories While Maintaining Old Ones

A new study funded by the National Institutes of Health uncovered patterns in the activation of old and new memories during sleep that keep these memories separate.

Medical professional holding a tablet computer.
Predictive Models Show Promise in Preventing Suicide

In a study funded by the National Institutes of Health, researchers created new suicide risk prediction models using data in electronic health records from the Indian Health Service.

A 3D view of an atypical multi-synaptic bouton
Study Illuminates the Structural Features of Memory Formation at the Cellular and Subcellular Levels

In a study supported by NIMH, researchers revealed the structural underpinnings of memory formation across a broad network of neurons in the mouse brain.

DNA strand.
Study Illuminates the Genetic Architecture of Bipolar Disorder

Largest-ever genome-wide study of a diverse group of people with bipolar disorder sheds new light on the genetic architecture underlying the disorder.

Sarah Hollingsworth Lisanby, M.D.
Dr. Sarah Hollingsworth Lisanby to Depart NIMH

Sarah Hollingsworth “Holly” Lisanby, M.D., Director of the Division of Translational Research, will depart NIMH this spring to join Arizona State University.

Integrated Chronic Care Clinics for Depression (IC3D) trial team
Integrated Care for Depression Yields Extended Benefits, Malawi Study Shows

An NIMH-funded study showed that incorporating depression treatment into care for chronic health conditions improved well-being for both patients and their families.