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Transforming the understanding
and treatment of mental illnesses.

Science News About Post-Traumatic Stress Disorder (PTSD)

Group of health care professionals standing in a circle and conferring over paperwork.
Collaborative Care Could Help Reduce Disparities in Mental Health Treatment

In an NIMH-funded study, a comprehensive collaborative care intervention significantly reduced post-traumatic stress disorder (PTSD) symptoms among trauma patients from racial and ethnic minority backgrounds.

Illustration of a DNA helix over top of a human brain
Scientists Map Networks Regulating Gene Function in the Human Brain

An NIMH-funded research consortium has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders.

Photograph of a man staring straight ahead with the sides of his face blurry and out of focus
Feelings of Detachment After Trauma May Signal Worse Mental Health Outcomes

A new NIMH-supported study shows that experiencing persistent feelings of detachment following trauma is an early psychological and biological marker of worse mental health outcomes.

illustration of human brain seen from above
Brain Activity Patterns After Trauma May Predict Long-Term Mental Health

The way a person’s brain responds to stress following a traumatic event, such as a car accident, may help to predict their long-term mental health outcomes, according to NIMH-supported research.

fear lab trainees with poster at SFN 2018
Puerto Rico’s “Fear Lab” Mentors Neuroscience Rigor amid Diversity

A lineage of young neuroscientists from diverse backgrounds trace their scientific roots to a “fear lab” in Puerto Rico that the National Institutes of Health has been supporting for two decades.

An fMRI image of the brain showing two small red areas that represent the amygdala, as defined functionally by the researchers.
Brain Biomarkers Could Help Identify Those at Risk of Severe PTSD

This study has shed light on the neurocomputational contributions to the development of post-traumatic stress disorder in combat veterans, finding distinct patterns for how the brain and body respond to learning danger and safety depending on the severity of PTSD symptoms.

hand holding pen writing on tablet
A Shorter—but Effective—Treatment for PTSD

Research supported by the National Institute of Mental Health has shown that a shorter therapy (written exposure therapy) may be just as effective as lengthier first-line treatments for PTSD.

zebrafish brain
Brain’s Alertness Circuitry Conserved Through Evolution

Using a molecular method likely to become widely adopted by the field, researchers have discovered brain circuitry essential for alertness – and for brain states more generally.

Brain imaging Fonzo
Imaging Pinpoints Brain Circuits Changed by PTSD Therapy

Using brain imaging to track the effects of treatment of post-traumatic stress disorder (PTSD), scientists have identified a brain circuit on which a frequently used and effective psychotherapy (prolonged exposure) acts to quell symptoms. The findings help explain why the neural circuit identified is a promising target for additional treatment development, including brain stimulation therapies.

National Institute of Mental Health
NIMH-Funded Study to Track the Effects of Trauma

By carefully tracking 5,000 people after they have experienced a traumatic event, a just-launched NIMH-funded study aims to provide a finely detailed map of the array of factors that play a role in the development of mental disorders that occur in the wake of trauma.

Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS)
Attention-Control Video Game Curbs Combat Vets’ PTSD Symptoms

A video game that implicitly taught combat vets that threatening stimuli are irrelevant to performing their task reduced their PTSD symptoms.

Ronald Kessler, Ph.D., of Harvard University
Girls Thrive Emotionally, Boys Falter After Move to Better Neighborhood

Girls in public housing benefited emotionally from a move to a better neighborhood while boys fared worse than if they’d stayed in the poor neighborhood. Rates of depression and conduct disorder markedly increased in boys and decreased in girls. Boys also experienced significantly increased rates of post-traumatic stress disorder (PTSD), complicating housing policy decision-making.