Science News About Autism Spectrum Disorder (ASD)

A tablet-based screening tool that analyzes children’s behavior in response to specific video clips shows promise for enhancing early autism screening, according to a study supported by NIMH.

In this NIMH-supported study, researchers investigated the neural underpinnings of sensory hypersensitivity in SCN2A-associated autism.

Persistent, collective efforts in the research community show how making early autism screening part of routine health care can support the well-being of children and families.

Susan A. Daniels, Ph.D. has been appointed as the HHS National Autism Coordinator and Director of the Office of National Autism Coordination (ONAC).

Research supported by NIMH suggests that children’s health records may yield some promising insights that could improve the accuracy of early autism screening.

An NIMH-supported study shows that preference for geometric images may be robust enough to serve as a biomarker for identifying some young children with autism.

The National Institutes of Health (NIH) is pleased to announce the winners of 2022 Speaking Up About Mental Health! This Is My Story essay contest.

The National Institutes of Health has awarded a total of $100 million over the next five years to support nine Autism Centers of Excellence. This endeavor funds large research projects to understand and develop interventions for autism spectrum disorder.

In an NIMH-supported study, researchers found that toddlers respond to emotionally expressive speech in different ways, and these varied responses are linked with their social, linguistic, and cognitive abilities.

An NIMH-supported study shows that incorporating a multistage screening process for autism spectrum disorder (ASD) into federally funded early intervention services may reduce disparities in early ASD diagnosis.

A recent study of gene networks may hold some promising clues about shared mechanisms underlying autism spectrum disorder and congenital heart disease, two physiologically distinct disorders that often co-occur.

NIMH researchers examine what people with ASD and people without ASD look at when viewing a social scene.

National Autism Coordinator Ann E. Wagner, Ph.D., will retire from federal service on June 30, 2021—Susan A. Daniels, Ph.D., will serve as Acting National Autism Coordinator beginning on July 1, 2021, and until a permanent successor is named.

A mobile app was successful at distinguishing toddlers diagnosed with autism spectrum disorder (ASD) from typically developing toddlers based on their eye movements while watching videos, according to a study funded by the National Institutes of Health.

NIMH, along with other NIH Institutes, is supporting the ABC-CT project, a multisite study that aims to test and refine biomarkers that can be used as objective measures of social impairment for children with autism in clinical trials, leading to more predictive and personalized treatment.

NIMH, along with other NIH Institutes, is supporting the goal of identifying autism in the first year of life by funding projects that seek to seek to translate findings related to early-emerging signs of autism into practical ASD screening tools that can be implemented in the general population and community settings.

Researchers were able to identify different types of rare genetic variations associated with autism spectrum disorder by analyzing data shared via the NIMH-funded Autism Sequencing Consortium.

The National Institutes of Health (NIH) has awarded more than four million dollars in FY 2019 to support seven research projects aimed at developing and validating screening tools to detect signs of autism spectrum disorder in the first year of life.

A new study in rodents has demonstrated, for the first time, that the brain’s cerebellum plays a role in controlling reward and social preference behavior—findings that shed light on the brain circuits critical to the affective and social dysfunction seen across multiple psychiatric disorders.

PsychENCODE researchers are discovering the biological mechanisms by which mental illness risk genes work in the human brain.

High levels of maternal inflammation during pregnancy have been linked to effects in children, including reduced brain circuit communications and altered long-distance brain wiring at birth, poorer cognitive function at one year – and to reduced impulse control and working memory at two years.

Young people with autism unknowingly tuned up flagging neural connections by playing a picture puzzle game that was rigged by their own brain activity.

A new study has identified an association between paternally-inherited rare structural variants in noncoding segments of genes and the development of autism spectrum disorder (ASD). The study adds to a growing body of research describing genetic contributors to ASD.

Depression, schizophrenia and autism spectrum disorder share some of the same patterns of suspect gene expression – molecular signatures.

NIMH’s Dr. Ann Wagner has been designed as the National Autism Coordinator. In this role, she will play a vital role in ensuring the implementation of national autism spectrum disorder research, services, and support activities across federal agencies.

Researchers have produced the first direct evidence that parts of our brains implicated in mental disorders may be shaped by a “residual echo” from our ancient past. The more a person’s genome carries genetic vestiges of Neanderthals, the more certain parts of his or her brain and skull resemble those of humans’ evolutionary cousins that went extinct 40,000 years ago.

Functional connectivity magnetic resonance imaging (fcMRI) may predict which high-risk, 6-month old infants will develop autism spectrum disorder (ASD) by age 2 years.

For the first time, neuroscientists have boosted a female rodent’s partnering with a male by stimulating connectivity of a brain reward circuit. Understanding the circuitry of such affiliative behaviors may lead to improved treatments for social impairment in severe mental disorders, such as autism spectrum disorder.

Neuroscientists have created a 3D window into the human brain’s budding executive hub assembling itself during a critical period in prenatal development.

Researchers have discovered a pattern of genetic glitches and behavioral features, such as delayed walking, in some cases of autism spectrum disorder (ASD) that could ultimately lead to identification of subgroups and improved treatment.

Researchers have narrowed suspected genetic causes of autism and related developmental disabilities by ruling out what they call the “noise of benign variation.”

Schizophrenia, autism risk gene trajectories point to shared causes

Two of the world’s largest brain tissue banks unify efforts to collect and distribute a critical number of brain donations for important autism research.

James McPartland, Ph.D. of Yale University will lead a new four-year $28 million Biomarkers Consortium project that aims to improve clinical evaluation of treatments for social impairment in children with autism.

Dr. Insel describes recent accomplishments related to autism spectrum disorder over the past year—from the reauthorization of the Interagency Autism Coordinating Committee to promising therapeutic results from clinical trials.

Many patients with psychosis develop health risks associated with premature death early in the course of their mental illness, researchers have found.

NIH-funded projects aim at improving access, timeliness of interventions.

Most of the genetic risk for autism comes from versions of genes that are common in the population rather than from rare variants or spontaneous glitches.

NIMH Twitter Chat on Autism Spectrum Disorder Diagnosis

The architecture of the autistic brain is speckled with patches of abnormal neurons, according to research partially funded by the National Institute of Mental Health, published in the New England Journal of Medicine on March 27, 2014.

The hippocampus houses learning and memory—specifically the storage of knowledge of who, what, where, and when. Using a special transgenic mouse, researchers have now pinpointed a hippocampal region called CA2 that is important for social memory, the ability of animal to recognize another of the same species. Understanding this region could be useful in understanding and treating disorders characterized by altered social behaviors such as schizophrenia, bipolar disorder, and autism.