HIV Prevention and Treatment Implementation Science Program

Overview

This program encourages research to enhance the uptake, effectiveness and efficiency of evidence-based interventions, and to inform and enhance the effectiveness and efficiency of interventions currently available in the continuum of HIV prevention, HIV testing, and HIV care, to maximize community impact. Research is especially encouraged that aligns with the goals of the End the HIV Epidemic (EHE) initiative in the United States.

Significant progress is needed to create generalizable knowledge regarding implementation approaches, transfer interventions from one setting or population to another, and to make informed choices between competing interventions to maximize their effect in target populations. This gap between research and implementation is impeding success in prevention, care, and treatment programs in the number of people reached and effects on health outcomes. Advances are urgently needed to reduce these unknowns and increase the public health impact of HIV/AIDS prevention, treatment, and care services.

Areas of Emphasis

Research projects are encouraged that address the uptake, effectiveness, efficiency, and outcomes for individual or combination HIV prevention and treatment interventions. Studies include:

• The prevention capacity of systems, providers, or operational tools to target evidence-based interventions (EBIs) to the persons most affected by HIV in their communities;
• The study of implementation approaches (uptake, effectiveness, efficiency) of individual and/or combination prevention EBIs (e.g., PMTCT, behavioral/social risk-reduction, male circumcision, PrEP, condom provision), designed to maximize the optimal targeting, uptake, coverage, effectiveness, and efficiency of service provision;
• The implementation (uptake, effectiveness, efficiency) of individual and/or combination EBIs designed to maximize HIV testing, linkage to HIV care, earlier treatment initiation, adherence and engagement HIV testing, including advancements in approaches and technologies;
• The impact of varying models of differentiated HIV care on HIV care continuum outcomes, including studies to evaluate optimal approaches to integrate HIV prevention, care, and treatment into community care with related services (sexually transmitted infections, family planning, prenatal care, malaria, tuberculosis);
• The implementation of targeted interventions designed to reduce documented racial/ethnic, gender, and age-related disparities in HIV prevention and treatment outcomes.

Contact

Christopher Gordon, Ph.D.
240-627-3867, cgordon1@mail.nih.gov