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Transforming the understanding
and treatment of mental illnesses.

Genetic Epidemiology Research Branch (GEB-SDGE)

Research Interests

Mood and anxiety disorders that GEB researches include

  • Major depression
  • Bipolar disorder (manic depression)
  • Generalized anxiety disorder (GAD)
  • Social anxiety disorder/social phobia
  • Panic disorder
  • Obsessive-compulsive disorder (OCD)
  • Post-traumatic stress disorder (PTSD) 

The major research goals of GEB are

  • To conduct studies of families to identify aspects of mental disorders that are inherited;
  • To determine the reasons why mood and anxiety disorders may exist in association with other mental disorders (e.g., alcoholism, substance abuse) and medical disorders (migraine);
  • To identify the early expression of mental disorders in the population by following children of parents with these disorders;
  • To conduct pilot studies of programs aimed at preventing mood and anxiety disorders in youth;
  • To develop and apply study designs and statistical methods to identify how an interaction of genes and the environment contribute to mental disorders. Studies include half-siblings, step-siblings, children of twins, and migrant studies (i.e., people who have moved from one geographic area to another).