Recent Publications

Real-time mobile monitoring of bipolar disorder: a review of evidence and future directions. Dunster GP, Swendsen J, Merikangas KR. Neuropsychopharmacology. 2020 Sep 12. PMID: 32919408 

Comorbidity and patterns of familial aggregation in attention-deficit/hyperactivity disorder and bipolar disorder in a family study of affective and anxiety spectrum disorders. Walsh RFL, Sheppard B, Cui L, Brown C, Van Meter A, Merikangas KR. J Psychiatr Res. 2020 Aug 23;130:355-361. PMID: 32882577 

The Coronavirus Health and Impact Survey (CRISIS) reveals reproducible correlates of pandemic-related mood states across the Atlantic. Nikolaidis A, Paksarian D, Alexander L, DeRosa J, Dunn J, Nielson DM, Droney I, Kang M, Douka I, Bromet E, Milham MP, Stringaris A, Merikangas KR. medRxiv. 2020 Aug 27: 2020. PMID: 32869041 

Psychopathological precursors of the onset of mood disorders in offspring of parents with and without mood disorders: results of a 13-year prospective cohort high-risk study. Rudaz D, Vandeleur CL, Gholam M, Castelao E, Strippoli MF, Marquet P, Aubry JM, Merikangas KR, Preisig M. J Child Psychol Psychiatry. 2020 Aug 25. PMID: 32841378 

Validation and feasibility of the ASQ among pediatric medical and surgical inpatients. Horowitz LM, Wharff EA, Mournet AM, Ross AM, McBee-Strayer S, He JP, Lanzillo EC, White E, Bergdoll E, Powell DS, Solages M, Merikangas KR, Pao M, Bridge JA. Hosp Pediatr. 2020 Sep;10(9):750-757. PMID: 32826283 

Mood disorders, childhood maltreatment, and medical morbidity in US adults: an observational study. Stapp EK, Williams SC, Kalb LG, Holingue CB, Van Eck K, Ballard ED, Merikangas KR, Gallo JJ. J Psychosom Res. 2020 Jul 28;137:110207. PMID: 32745641 

Association of outdoor artificial light at night with mental disorders and sleep patterns among US adolescents. Paksarian D, Rudolph KE, Stapp EK, Dunster GP, He J, Mennitt D, Hattar S, Casey JA, James P, Merikangas KR. JAMA Psychiatry. 2020 Jul 8:e201935. PMID: 32639562 

Validation of the Ask Suicide-Screening Questions for adult medical inpatients: a brief tool for all ages. Horowitz LM, Snyder DJ, Boudreaux ED, He JP, Harrington CJ, Cai J, Claassen CA, Salhany JE, Dao T, Chaves JF, Jobes DA, Merikangas KR, Bridge JA, Pao M. Psychosomatics. 2020 Apr 28:S0033-3182(20)30120-1. PMID: 32487323 

Problematic internet use in children and adolescents: associations with psychiatric disorders and impairment. Restrepo A, Scheininger T, Clucas J, Alexander L, Salum GA, Georgiades K, Paksarian D, Merikangas KR, Milham MP. BMC Psychiatry. 2020 May 27;20(1):252. PMID: 32456610 

Parental bipolar disorder, family environment, and offspring psychiatric disorders: a systematic review. Stapp EK, Mendelson T, Merikangas KR, Wilcox HC. J Affect Disord. 2020 May 1;268:69-81. Epub 2020 Mar 3. PMID: 32158009 

Adolescent residential mobility, genetic liability and risk of schizophrenia, bipolar disorder and major depression. Paksarian D, Trabjerg BB, Merikangas KR, Mors O, Børglum AD, Hougaard DM, Nordentoft M, Werge T, Pedersen CB, Mortensen PB, Agerbo E, Horsdal HT. Br J Psychiatry. 2020 Jul;217(1):390-396. PMID: 32024557 

The number of biological parents with alcohol use disorder histories and risk to offspring through age 30. Kosty DB, Farmer RF, Seeley JR, Merikangas KR, Klein DN, Gau JM, Duncan SC, Lewinsohn PM. Addict Behav. 2020 Mar;102:106196. Epub 2019 Oct 31. PMID: 31783247 

Symptom trajectories in the months before and after a suicide attempt in individuals with bipolar disorder: A STEP-BD study. Ballard ED, Farmer CA, Shovestul B, Vande Voort J, Machado-Vieira R, Park L, Merikangas KR, Zarate CA Jr. Bipolar Disord. 2020 May;22(3):245-254. Epub 2019 Dec 9. PMID: 31737973 

Trends in the prevalence and incidence of attention-deficit/hyperactivity disorder among adults and children of different racial and ethnic groups. Chung W, Jiang SF, Paksarian D, Nikolaidis A, Castellanos FX, Merikangas KR, Milham MP. JAMA Netw Open. 2019 Nov 1;2(11):e1914344. PMID: 31675080 

Major depression subtypes are differentially associated with migraine subtype, prevalence and severity. Pisanu C, Lundin E, Preisig M, Gholam-Rezaee M, Castelao E, Pistis G, Merikangas KR, Glaus J, Squassina A, Del Zompo M, Schiöth HB, Mwinyi J. Cephalalgia. 2020 Apr;40(4):347-356. Epub 2019 Oct 24. PMID: 31645113 

Environmental noise and sleep and mental health outcomes in a nationally representative sample of urban US adolescents. Rudolph KE, Shev A, Paksarian D, Merikangas KR, Mennitt DJ, James P, Casey JA. Environ Epidemiol. 2019 Aug 13;3(4):e056. eCollection 2019 Aug. PMID: 31538137 

Sleep, circadian rhythm, and physical activity patterns in depressive and anxiety disorders: A 2-week ambulatory assessment study. Difrancesco S, Lamers F, Riese H, Merikangas KR, Beekman ATF, van Hemert AM, Schoevers RA, Penninx BWJH. Depress Anxiety. 2019 Oct;36(10):975-986. Epub 2019 Jul 26. PMID: 31348850 

Harnessing progress in psychiatric genetics to advance population mental health. Merikangas KR, Merikangas AK. Am J Public Health. 2019 Jun;109(S3):S171-S175. PMID: 31242010 

Patterns and predictors of family environment among adolescents at high and low risk for familial bipolar disorder. Stapp EK, Musci RJ, Fullerton JM, Glowinski AL, McInnis M, Mitchell PB, Hulvershorn LA, Ghaziuddin N, Roberts GMP, Merikangas KR, Nurnberger JI Jr, Wilcox HC. J Psychiatr Res. 2019 Jul;114:153-160. Epub 2019 May 3. PMID: 31078786 

Familial aggregation and coaggregation of suicide attempts and comorbid mental disorders in adults. Ballard ED, Cui L, Vandeleur C, Castelao E, Zarate CA Jr, Preisig M, Merikangas KR. JAMA Psychiatry. 2019 Mar 27;76(8):826-33. PMID: 30916728 

Prevalence and correlates of hypersomnolence symptoms in US teens. Kolla BP, He JP, Mansukhani MP, Kotagal S, Frye MA, Merikangas KR. J Am Acad Child Adolesc Psychiatry. 2019 Jul;58(7):712-720. Epub 2018 Oct 30. PMID: 30768408 

Association between mood disorders and BMI/overweight using a family study approach. Glaus J, Cui L, Hommer R, Merikangas KR. J Affect Disord. 2019 Apr 1;248:131-138. Epub 2019 Jan 15. PMID: 30731280 

Social functioning and suicide risk in a community sample of adolescents. Van Meter AR, Paksarian D, Merikangas KR. J Clin Child Adolesc Psychol. 2019 Mar-Apr;48(2):273-287. Epub 2019 Jan 16. PMID: 30648897 

Causal mediation analysis with observational data: considerations and illustration examining mechanisms linking neighborhood poverty to adolescent substance use. Rudolph KE, Goin DE, Paksarian D, Crowder R, Merikangas KR, Stuart EA. Am J Epidemiol. 2019 Mar 1;188(3):598-608. PMID: 30561500 

Real-time mobile monitoring of the dynamic sssociations among motor activity, energy, mood, and sleep in adults with bipolar disorder. Merikangas KR, Swendsen J, Hickie IB, Cui L, Shou H, Merikangas AK, Zhang J, Lamers F, Crainiceanu C, Volkow ND, Zipunnikov V. JAMA Psychiatry.   2019 Feb 1;76(2):190-198. PMID: 30540352 

Differences between unipolar mania and bipolar-I disorder: evidence from nine epidemiological studies. Angst J, Rössler W, Ajdacic-Gross V, Angst F, Wittchen HU, Lieb R, Beesdo-Baum K, Asselmann E, Merikangas KR, Cui L, Andrade LH, Viana MC, Lamers F, Penninx BW, de Azevedo Cardoso T, Jansen K, Dias de Mattos Souza L, Azevedo da Silva R, Kapczinski F, Grobler C, Gholam-Rezaee M, Preisig M, Vandeleur CL. Bipolar Disord. 2019 Aug;21(5):437-448. Epub 2018 Dec 14. PMID: 30475430 

Physical-mental comorbidity of pediatric migraine in the Philadelphia Neurodevelopmental Cohort. Lateef T, He JP, Nelson K, Calkins ME, Gur R, Gur R, Merikangas KR. J Pediatr. 2019 Feb;205:210-217. Epub 2018 Oct 29. PMID: 30384971 

Mood reactivity and affective dynamics in mood and anxiety disorders. Lamers F, Swendsen J, Cui L, Husky M, Johns J, Zipunnikov V, Merikangas KR. J Abnorm Psychol. 2018 Oct;127(7):659-669. PMID: 30335438 

Physical activity and mental disorder among adolescents in the United States. He JP, Paksarian D, Merikangas KR. J Adolesc Health. 2018 Nov;63(5):628-635. Epub 2018 Aug 29. PMID: 30170937 

Clinical features associated with an increased risk for alcohol use disorders among family members. Farmer RF, Seeley JR, Gau JM, Klein DN, Merikangas KR, Kosty DB, Duncan SC, Lewinsohn PM. Psychol Addict Behav. 2018 Sep;32(6):628-638. Epub 2018 Aug 30. PMID: 30160501 

Bipolar spectrum in major depressive disorders. Angst J, Merikangas KR, Cui L, Van Meter A, Ajdacic-Gross V, Rössler W. Eur Arch Psychiatry Clin Neurosci. 2018 Dec;268(8):741-748. Epub 2018 Jul 21. PMID: 30032467 

Factorial structure and familial aggregation of the Hypomania Checklist-32 (HCL-32): results of the NIMH Family Study of Affective Spectrum Disorders. Glaus J, Van Meter A, Cui L, Marangoni C, Merikangas KR. Compr Psychiatry. 2018 Jul;84:7-14. Epub 2018 Apr 3. PMID: 29655654 

Time trends in the global prevalence of mental disorders in children and adolescents: gap in data on US youth. Merikangas KR. J Am Acad Child Adolesc Psychiatry. 2018 May;57(5):306-307. PMID: 29706158 

Racial disparities in bipolar disorder treatment and research: a call to action. Akinhanmi MO, Biernacka JM, Strakowski SM, McElroy SL, Balls Berry JE, Merikangas KR, Assari S, McInnis MG, Schulze TG, LeBoyer M, Tamminga C, Patten C, Frye MA. Bipolar Disord. 2018 Sep;20(6):506-514. Epub 2018 Mar 12. PMID: 29527766 

Olfactory processing in bipolar disorder, major depression, and anxiety. Kamath V, Paksarian D, Cui L, Moberg PJ, Turetsky BI, Merikangas KR. Bipolar Disord. 2018 Sep;20(6):547-555. Epub 2018 Feb 13. PMID: 29441710 

Prevalence of mental disorder and service use by immigrant generation and race/ethnicity among US adolescents. Georgiades K, Paksarian D, Rudolph KE, Merikangas KR. J Am Acad Child Adolesc Psychiatry. 2018 Apr;57(4):280-287.e2. Epub 2018 Feb 15. PMID: 29588054 

An open resource for transdiagnostic research in pediatric mental health and learning disorders. Alexander LM, Escalera J, Ai L, Andreotti C, Febre K, Mangone A, Vega-Potler N, Langer N, Alexander A, Kovacs M, Litke S, O'Hagan B, Andersen J, Bronstein B, Bui A, Bushey M, Butler H, Castagna V, Camacho N, Chan E, Citera D, Clucas J, Cohen S, Dufek S, Eaves M, Fradera B, Gardner J, Grant-Villegas N, Green G, Gregory C, Hart E, Harris S, Horton M, Kahn D, Kabotyanski K, Karmel B, Kelly SP, Kleinman K, Koo B, Kramer E, Lennon E, Lord C, Mantello G, Margolis A, Merikangas KR, Milham J, Minniti G, Neuhaus R, Levine A, Osman Y, Parra LC, Pugh KR, Racanello A, Restrepo A, Saltzman T, Septimus B, Tobe R, Waltz R, Williams A, Yeo A, Castellanos FX, Klein A, Paus T, Leventhal BL, Craddock RC, Koplewicz HS, Milham MP.Sci Data. 2017 Dec 19;4:170181. PMID: 29257126 

The bidirectional relationship between anxiety disorders and circulating levels of inflammatory markers: results from a large longitudinal population-based study. Glaus J, von Känel R, Lasserre AM, Strippoli MF, Vandeleur CL, Castelao E, Gholam-Rezaee M, Marangoni C, Wagner EN, Marques-Vidal P, Waeber G, Vollenweider P, Preisig M, Merikangas KR. Depress Anxiety. 2018 Apr;35(4):360-371. Epub 2017 Dec 15. PMID: 29244900 

Generalizability of clinical trial results for adolescent major depressive disorder. Blanco C, Hoertel N, Franco S, Olfson M, He JP, López S, González-Pinto A, Limosin F, Merikangas KR. Pediatrics. 2017 Dec;140(6):e20161701. Epub 2017 Nov 2. PMID: 29097612 

Parenting style and mental disorders in a nationally representative sample of US adolescents. Eun JD, Paksarian D, He JP, Merikangas KR. Soc Psychiatry Psychiatr Epidemiol. 2018 Jan;53(1):11-20. Epub 2017 Nov 6. PMID: 29110024 

Mood disorders and circulating levels of inflammatory markers in a longitudinal population-based study. Glaus J, von Känel R, Lasserre AM, Strippoli MF, Vandeleur CL, Castelao E, Gholam-Rezaee M, Marangoni C, Wagner EN, Marques-Vidal P, Waeber G, Vollenweider P, Preisig M, Merikangas KR. Psychol Med. 2017 Sep 20:1-13. PMID: 28929992 

A genetic risk score is differentially associated with migraine with and without aura. Pisanu C, Preisig M, Castelao E, Glaus J, Pistis G, Squassina A, Del Zompo M, Merikangas KR, Waeber G, Vollenweider P, Mwinyi J, Schiöth HB. Hum Genet. 2017 Aug;136(8):999-1008. PMID: 28656458

Dysregulation of objectively assessed 24-hour motor activity patterns as a potential marker for bipolar I disorder: results of a community-based family study. Paksarian D, Trabjerg BB, Merikangas KR, Mors O, Børglum AD, Hougaard DM, McGrath JJ, Pedersen CB, Mortensen PB, Agerbo E. Psychol Med. 2017 Jun 29:1-10. PMID: 28659227 

The role of genetic liability in the association of urbanicity at birth and during upbringing with schizophrenia in Denmark. Paksarian D, Trabjerg BB, Merikangas KR, Mors O, Børglum AD, Hougaard DM, McGrath JJ, Pedersen CB, Mortensen PB, Agerbo E. Psychol Med. 2017 Jun 29:1-10. PMID: 28659227 

Neurocognitive performance as an endophenotype for mood disorder subgroups. Merikangas AK, Cui L, Calkins ME, Moore TM, Gur RC, Gur RE, Merikangas KR. J Affect Disord. 2017 Jun;215:163-171. PMID: 28340442 

Future Surveillance of Mental Disorders in the United States: Count People, Not Disorders. Merikangas KR, Bromet EJ, Druss BG. JAMA Psychiatry. 2017 May 1;74(5):431-432. PMID: 28329225 

Stability and change in reported age of onset of depression, back pain, and smoking over 29 years in a prospective cohort study. Paksarian D, Cui L, Angst J, Ajdacic-Gross V, Rössler W, Merikangas KR. J Psychiatr Res. 2017 May;88:105-112. PMID: 28113111 

High leptin levels are associated with migraine with aura. Pisanu C, Preisig M, Castelao E, Glaus J, Cunningham JL, Del Zompo M, Merikangas KR, Schiöth HB, Mwinyi J. Cephalalgia. 2017 Apr;37(5):435-441. PMID: 27165492 

Sleep Patterns and Mental Health Correlates in US Adolescents. Zhang J, Paksarian D, Lamers F, Hickie IB, He J, Merikangas KR. J Pediatr. 2017 Mar;182:137-143. PMID: 27939122 

Persistence of psychosis spectrum symptoms in the Philadelphia Neurodevelopmental Cohort: a prospective two-year follow-up. Calkins ME, Moore TM, Satterthwaite TD, Wolf DH, Turetsky BI, Roalf DR, Merikangas KR, Ruparel K, Kohler CG, Gur RC, Gur RE. World Psychiatry. 2017 Feb;16(1):62-76. PMID: 28127907 

Activation in Bipolar Disorders: A Systematic Review. Scott J, Murray G, Henry C, Morken G, Scott E, Angst J, Merikangas KR, Hickie IB. JAMA Psychiatry. 2017 Feb 1;74(2):189-196. PMID: 28002572 

Reexamining associations between mania, depression, anxiety and substance use disorders: results from a prospective national cohort. Olfson M, Mojtabai R, Merikangas KR, Compton WM, Wang S, Grant BF, Blanco C. Mol Psychiatry. 2017 Feb;22(2):235-241. PMID: 27137742 

Correlates of Overweight and Obesity Among Adolescents With Bipolar Disorder in the National Comorbidity Survey-Adolescent Supplement (NCS-A). Goldstein BI, Blanco C, He JP, Merikangas K. J Am Acad Child Adolesc Psychiatry. 2016 Dec;55(12):1020-1026. PMID: 27871636 

Familial aggregation and heritability of the melancholic and atypical subtypes of depression. Lamers F, Cui L, Hickie IB, Roca C, Machado-Vieira R, Zarate CA Jr, Merikangas KR. J Affect Disord. 2016 Nov 1;204:241-6. PMID: 27450632 

Latent Trajectories of Common Mental Health Disorder Risk Across 3 Decades of Adulthood in a Population-Based Cohort. Paksarian D, Cui L, Angst J, Ajdacic-Gross V, Rössler W, Merikangas KR. JAMA Psychiatry. 2016 Oct 1;73(10):1023-1031. PMID: 27602550 

Medical Comorbidity of Attention-Deficit/Hyperactivity Disorder in US Adolescents. Jameson ND, Sheppard BK, Lateef TM, Vande Voort JL, He JP, Merikangas KR. J Child Neurol. 2016 Oct;31(11):1282-9. PMID: 27334310 

Prevalence of migraine in a diverse community--electronic methods for migraine ascertainment in a large integrated health plan. Pressman A, Jacobson A, Eguilos R, Gelfand A, Huynh C, Hamilton L, Avins A, Bakshi N, Merikangas K. Cephalalgia. 2016 Apr;36(4):325-34. PMID: 26069243 

Association of Lifetime Mental Disorders and Subsequent Alcohol and Illicit Drug Use: Results From the National Comorbidity Survey-Adolescent Supplement. Conway KP, Swendsen J, Husky MM, He JP, Merikangas KR. J Am Acad Child Adolesc Psychiatry. 2016 Apr;55(4):280-8. PMID: 27015718 

Disruptive Mood Dysregulation Disorder at Ages 13-18: Results from the National Comorbidity Survey-Adolescent Supplement. Althoff RR, Crehan ET, He JP, Burstein M, Hudziak JJ, Merikangas KR. J Child Adolesc Psychopharmacol. 2016 Mar;26(2):107-13. PMID: 26771536 

The epidemiology of common mental disorders from age 20 to 50: results from the prospective Zurich cohort Study. Angst J, Paksarian D, Cui L, Merikangas KR, Hengartner MP, Ajdacic-Gross V, Rössler W. Epidemiol Psychiatr Sci. 2016 Feb;25(1):24-32. PMID: 25802979 

Racial-ethnic disparities in empirically-derived subtypes of subclinical psychosis among a U.S. sample of youths. Paksarian D, Merikangas KR, Calkins ME, Gur RE. Schizophr Res. 2016 Jan;170(1):205-10. PMID: 26711527 

The specificity of the familial aggregation of early-onset bipolar disorder: A controlled 10-year follow-up study of offspring of parents with mood disorders. Preisig M, Strippoli MF, Castelao E, Merikangas KR, Gholam-Rezaee M, Marquet P, Aubry JM, Vandeleur CL. J Affect Disord. 2016 Jan 15;190:26-33. PMID: 26480208
 

The Impact of Post-Traumatic Stress Disorder on the Burden of Migraine: Results From the National Comorbidity Survey-Replication. Rao AS, Scher AI, Vieira RV, Merikangas KR, Metti AL, Peterlin BL. Headache. 2015 Nov-Dec;55(10):1323-41. PMID: 26473981 

School Start Time and Adolescent Sleep Patterns: Results From the U.S. National Comorbidity Survey--Adolescent Supplement. Paksarian D, Rudolph KE, He JP, Merikangas KR. Am J Public Health. 2015 Jul;105(7):1351-7. PMID: 25973803 

A population-based study of the risk of schizophrenia and bipolar disorder associated with parent-child separation during development. Paksarian D, Eaton WW, Mortensen PB, Merikangas KR, Pedersen CB. Psychol Med. 2015 Oct;45(13):2825-37. PMID: 25952483 

The Philadelphia Neurodevelopmental Cohort: constructing a deep phenotyping collaborative. Calkins ME, Merikangas KR, Moore TM, Burstein M, Behr MA, Satterthwaite TD, Ruparel K, Wolf DH, Roalf DR, Mentch FD, Qiu H, Chiavacci R, Connolly JJ, Sleiman PMA, Gur RC, Hakonarson H, Gur RE. J Child Psychol Psychiatry. 2015 Dec;56(12):1356-1369. PMID: 25858255 

Comorbidity of physical and mental disorders in the neurodevelopmental genomics cohort study. Merikangas KR, Calkins ME, Burstein M, He JP, Chiavacci R, Lateef T, Ruparel K, Gur RC, Lehner T, Hakonarson H, Gur RE. Pediatrics. 2015 Apr;135(4):e927-38. PMID: 25755242 

The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort. Robinson EB, Kirby A, Ruparel K, Yang J, McGrath L, Anttila V, Neale BM, Merikangas K, Lehner T, Sleiman PM, Daly MJ, Gur R, Gur R, Hakonarson H. Mol Psychiatry. 2015 Apr;20(4):454-8. PMID: 25023143 

Accuracy of family history reports of migraine in a community-based family study of migraine. Lateef TM, Cui L, Nakamura E, Dozier J, Merikangas K. Headache. 2015 Mar;55(3):407-12. PMID: 25676478 

Contrasting and convergent patterns of amygdala connectivity in mania and depression: a resting-state study. Li M, Huang C, Deng W, Ma X, Han Y, Wang Q, Li Z, Guo W, Li Y, Jiang L, Lei W, Hu X, Gong Q, Merikangas KR, Palaniyappan L, Li T. J Affect Disord. 2015 Mar 1;173:53-8. PMID: 25462396 

Health correlates of insomnia symptoms and comorbid mental disorders in a nationally representative sample of US adolescents. Blank M, Zhang J, Lamers F, Taylor AD, Hickie IB, Merikangas KR. Sleep. 2015;38(2):197-204. PMID: 25325502 

Treatment patterns of youth with bipolar disorder: results from the National Comorbidity Survey-Adolescent Supplement (NCS-A). Khazanov GK, Cui L, Merikangas KR, Angst J. J Abnorm Child Psychol. 2015 Feb;43(2):391-400. PMID: 24958307 

The space of common psychiatric disorders in adolescents: comorbidity structure and individual latent liabilities. Blanco C, Wall MM, He JP, Krueger RF, Olfson M, Jin CJ, Burstein M, Merikangas KR. J Am Acad Child Adolesc Psychiatry. 2015 Jan;54(1):45-52. PMID: 25524789 

Major depression in the national comorbidity survey-adolescent supplement: prevalence, correlates, and treatment. Avenevoli S, Swendsen J, He JP, Burstein M, Merikangas KR. J Am Acad Child Adolesc Psychiatry. 2015 Jan;54(1):37-44.e2. PMID: 25524788