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Transforming the understanding
and treatment of mental illnesses.

Suicide and the Brain

Join a Research Study: Enrolling nationally from around the country

To contact the study team email (moodresearch@mail.nih.gov) or call 1-877-646-3644 (1-877-MIND-NIH) [TTY: 711].

Find out if you are eligible by filling out this survey.

Learn more about our current studies here.

National Institute of Mental Health (NIMH) researchers seek adults 18 to 70, who have a history of attempted suicide but are not currently suicidal, for a research study of suicide and brain function. Participation includes up to seven days as an inpatient at the NIH Clinical Center in Bethesda, Maryland.

Procedures include blood tests, medical evaluations, brain imaging, sleep studies and psychiatric interviews. Some participants may be offered optional ketamine infusions, under investigational use for depression. Participants do not need to stop their current medications. Compensation and transportation are provided. Pregnant women and individuals with serious medical conditions are not eligible.

There is no cost to participate. We enroll eligible participants locally and from around the country. Travel arrangements are provided, and costs are covered by NIMH (arrangements vary by distance). After completing the study, participants receive short-term follow-up care at the NIH while transitioning back to a provider.

If you are in a crisis situation, contact your doctor's office, go to the nearest emergency room, or call 911 for emergency services. You can also call or text the 988 Suicide & Crisis Lifeline or go to 988lifeline.org. Trained staff can help talk you through your crisis.

Find out if you are eligible by filling out this survey.

Learn more about our current studies here.

To contact the study team email (moodresearch@mail.nih.gov) or call 1-877-646-3644 (1-877-MIND-NIH) [TTY: 711].

Study Identifiers

  • NIMH Protocol Number: 15-M-0188
  • ClinicalTrials.gov Study Number: 02543983 

Investigator(s): Carlos Zarate Jr, M.D.