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Transforming the understanding
and treatment of mental illnesses.

Depression and Suicide Related Behaviors Program

Overview

This program supports research on the neurodevelopmental trajectories and mechanisms of mental illness associated with affect regulation, emotion, and stress reactivity, including depression, non-suicidal self-injury, suicidal thoughts and behaviors, and related phenotypes in children and adolescents. Of interest are studies that examine the developmental course of, periods of vulnerability or sensitivity for, or risk processes related to the onset, progression, recurrence, and remission of these disorders and their relevant components. Of particular interest are studies that link brain development with behavioral development; studies that identify sensitive periods for typical and atypical developmental trajectories; studies that elucidate biomarkers and mechanisms of disease progression; studies delineating mechanisms of sex and gender differences in the development of these phenotypes; and studies that test integrative models incorporating multiple levels of analysis (biological, behavioral, and environmental) across multiple RDoC constructs.

Contact

Eric Murphy, Ph.D.
Program Chief
6001 Executive Boulevard, MSC 9617
301-443-9230, eric.murphy@nih.gov