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and treatment of mental illnesses.

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Goal Selection; Updating, Representation, and Maintenance

RDoC Classification

Domain: Cognitive Systems > Construct: Cognitive Control

Description

Goal selection refers the cognitive process of choosing among potential outcomes, actions, or behaviors, and can be considered as a component process of cognitive control.

Goal updating involves refreshing the cognitive content related to specific potential outcomes, actions, or behaviors, and can be considered a component process of cognitive control.

Goal Selection

Circuits

Frontopolar/Anterior LPFC (BA10)Inhibition of DMN

Self-Report

BRIEF (Gioa)

Paradigms

Badre tasksKoechlin paradigmTask switching

Updating, Representation, and Maintenance

Molecules

DopamineGABAGlutamateNorepinephrine

Cells

Pyramidal cells

Circuits

Dorsolateral Prefrontal CortexPosterior Parietal CortexThalamocortical

Physiology

Gamma synchronyPupilometry

Behavior

DistractibilityOff-task behaviors

Self-Report

BRIEF (Gioa)Cognitive Failures QuestionnaireSANS/SAPS/PANSS

Paradigms

AX paradigmsCued stimulus-response reversal tasksTask switchingTower tasks