Cordelia Hume

Cordelia is a post-baccalaureate IRTA Fellow in the Section on Behavioral Neuroscience at the NIMH. She earned her Bachelor of Science in Neuroscience with minors in Biology and Chemistry from Duke University in 2024. During her time at Duke, she worked with Dr. Ornit Chiba-Falek to research the transcriptomic risk factors of late-onset Alzheimer’s Disease. Cordelia also worked with a team led by Dr. Muhammad Zafar to access epilepsy awareness and knowledge amongst physicians and students in Pakistan. She then completed independent research for her honors thesis under the mentorship of Dr. Arsen Hunanyan and Dr. Mohammad Mikati, investigating the mechanisms of the progressive nature of the rare neurologic disease Alternating Hemiplegia of Childhood. In her free time, Cordelia enjoys hiking with friends, cooking, and knitting.

Peer-Reviewed Papers

Gamache J, Gingerich D, Shwab E K, Barrera J, Garrett M, Hume C, Crawford G, Ashley-Koch A, Chiba-Falek O. (2023) Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans-regulatory networks and their target genes in Alzheimer’s disease brains. Cell Biosci.13(1):185

Puia-Dumitrescu M, Younge N, Benjamin D, Lawson K, Hume C, Hill K, Mengistu J, Wilson A, Zimmerman K, Ahmad K, Greenberg R. (2020) Medications and in-hospital outcomes in infants born at 22-24 weeks of gestation. J Perinatol. 40(5):781-789

Presentations

Hume C, Hunanyan A, Verma A, Mikati M. Long-term behavioral effects of intracranial injections using isoflurane anesthesia on wild-type and on mutant Mashl_­+/- Mice. (2023). Duke Department of Neurology Research 2023 Retreat, Durham, NC; 2023 ATP1A3 Conference, Chicago, IL (abstract only)

Hume C, Hunanyan A, Mikati M. Investigating a potential mechanism for the progression of Alternating Hemiplegia of Childhood: Age-dependent Na+/K+=ATPase activity and behavioral symptoms in Mashl+/- mice. (2024) Duke Department of Neuroscience Graduating with Distinction Presentations, Durham, NC

Hwang J, Karthikeyan L, Hume C, .. Zafar M. Bridging the Treatment Gap in Epilepsy: A cross-sectional study of Pakistani physicans’ perceptions of barrier to care and self-reported competency. (2023). 2023 North Carolina Neurological Society Annual Conference; Duke University School of Medicine Department of Pediatrics 2023 Research Retreat (Virtual abstract acceptance: 2023 Child Neurology Society Conference, Vancouver, Canada)

Sabha N, Hume C, Mohammed S, Karthikeyan L, … Zafar M. Improving Epilepsy Education in Lower Middle Income Countries’ Schools: Reducing Misconceptions about Epilepsy to Improve Epilepsy Awareness in Pakistan and India. 2023 International Epilepsy Conference in Dublin, virtual; Duke University School of Medicine Department of Pediatrics 2023 Research Retreat, Durham, NC (Virtual abstract acceptance: 2023 Child Neurology Society Conference, Vancouver, Canada)

Verma A, Hunanyan A, Hume C, Mikati M. Cardiorespiratory Rate Downregulation in the Na+/K+-ATPase Sudden Unexpected Death in Epilepsy Model. 2023 Duke Department of Neurology Research Retreat, Durham, NC