Treatment of SSRI-resistant Depression in Adolescents (TORDIA)

The NIMH-funded Treatment of SSRI-resistant Depression in Adolescents (TORDIA) study is a multi-site, clinical research study examining treatment options for teens whose depression has not improved after one adequate trial of a selective serotonin reuptake inhibitor (SSRI), a type of antidepressant. This page provides information about the study.

News about the TORDIA study

• Science Update (April 4, 2011): Depressed Teens with History of Abuse Less Likely to Respond to Combination Treatment
• Science Update (December 2, 2010): Teens Who Recover from Hard-to-treat Depression Still at Risk for Relapse
• Science Update (May 26, 2010): Early Treatment Decisions Crucial for Teens with Treatment-resistant Depression
• Science Update (December 9, 2009): Substance Use Associated with Low Response to Depression Treatment Among Teens
• Science Update (February 17, 2009): Suicidal Thinking May Be Predicted Among Certain Teens with Depression
• Science Update (February 11, 2009): Getting Closer to Personalized Treatment for Teens with Treatment-resistant Depression
• Press Release (February 26, 2008): Teens with Treatment-resistant Depression More Likely to Get Better with Switch to Combination Therapy

Related Information

• Child and Adolescent Mental Health
• Depression in Children and Adolescents
• Depression
• Clinical trial information about the Treatment of SSRI-resistant Depression in Adolescents (TORDIA) study