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Science News about Bipolar Disorder

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Mice Expressing Human Genes Bred to Help Unravel Mental Disorders
June 26, 2008 • Science Update
New mouse strains engineered to express human genes related to mental disorders are being developed under a recently-launched grant program from NIMH's Division of Neuroscience and Basic Behavioral Science.
Potential New Target Found for Developing Medications to Treat Bipolar Disorder
June 20, 2008 • Science Update
Medications that target the protein BAG1, which regulates a process that can trigger symptoms in people who have bipolar disorder, may offer a new way of treating the disease, according to NIMH scientists.
New NIMH Research to Test Innovative Treatments for Children with ADHD
June 5, 2008 • Science Update
Two new grants funded by NIMH will focus on novel and innovative approaches to treating children who have attention deficit hyperactivity disorder (ADHD).
Imaging Identifies Brain Regions and Chemicals Underlying Mood Disorders; May Lead to Better Treatments
May 6, 2008 • Science Update
Recently developed imaging techniques allow the mapping of the brain circuits and chemical systems believed responsible for a range of mood abnormalities including depression and bipolar disorder, and hold promise for improved treatments, scientists say.
Bipolar Youths’ Misreading of Faces May be Risk Marker for Illness
March 4, 2008 • Science Update
Youngsters with pediatric bipolar disorder and healthy peers who have first-degree relatives with bipolar disorder share the same difficulty labeling facial emotions, NIMH researchers have discovered.
Tomorrow’s Antidepressants: Skip the Serotonin Boost?
February 14, 2008 • Science Update
Even when serotonin levels stayed low, scientists were able to correct abnormal, mental-illness-like behaviors in mice by blocking an enzyme called GSK3ß. The finding adds evidence that molecular targets other than serotonin may lead to better and faster medications for some mental illnesses.
Faster-Acting Medications for Bipolar Disorder’s Manic Phase May Be Feasible
January 23, 2008 • Science Update
Scientists may be able to develop faster-acting medications for the manic phase of bipolar disorder, new research shows.
Mood Disorders Predict Later Substance Abuse Problems
January 9, 2008 • Science Update
People with manic symptoms and bipolar disorder type II are at significant risk of later developing an alcohol abuse or dependence problem, a long-term study conducted in Switzerland confirms.
Bipolar Disorder Phenome Database May Aid Search for Related Genes
October 2, 2007 • Science Update
Early findings from the recently launched Bipolar Disorder Phenome Database were published in the August 2007 issue of the American Journal of Psychiatry.
Manic Phase of Bipolar Disorder Benefits from Breast Cancer Medication
September 12, 2007 • Press Release
The medication tamoxifen, best known as a treatment for breast cancer, dramatically reduces symptoms of the manic phase of bipolar disorder more quickly than many standard medications for the mental illness, a new study shows.
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