Clinical Trials
Miscellaneous Conditions
Featured Studies
Featured studies include only those currently recruiting participants. They are listed according to the date they were added to the ClinicalTrials.gov registry, with the most recent studies appearing first.
- Effectiveness of Anger Management Treatment in Reducing Anger-Related Behaviors in Female Juvenile Offenders.
Interventional study. This study will evaluate the effectiveness of an anger management treatment program, Juvenile Justice Anger Management for Girls, in reducing anger-related behaviors displayed by girls in the juvenile justice system. Ages 12-19. Location in Philadelphia, PA.
- Effectiveness of Flutamide in Treating Women With Premenstrual Dysphoric Disorder.
Interventional study. This study will evaluate the effectiveness of flutamide in reducing symptoms of premenstrual dysphoric disorder. Ages 18-48. Location in New York, NY.
- Effectiveness of School- and Home-Based Mental Health Services in Improving Learning and Behavior in Children in Urban Schools.
Interventional study. This study will evaluate the effectiveness of school- and home-based mental health services and training modules in supporting learning and behavior in financially disadvantaged children who live in urban areas. Ages 5-12. Location in Chicago, IL.
- Effectiveness of Collaborative Services in Primary Care for Treating Children With Behavior Disorders.
Interventional study. This study will evaluate the effectiveness of a doctor-office collaborative care approach in treating children with disruptive behavior problems in the pediatric primary care setting. Ages 5-12. Location in Pittsburgh, PA.
- Evaluating the Effectiveness of Sertraline in Treating Women With Premenstrual Dysphoric Disorder.
Interventional study. This study will evaluate the effectiveness of sertraline in reducing symptoms in women diagnosed with premenstrual dysphoric disorder. Ages 18-48. Locations in New Haven, CT; New York, NY; Richmond, VA.
- Comparing the Effectiveness of Two Family-Based Therapies in Treating Young Children With Obsessive-Compulsive Disorder.
Interventional study. This study will compare the effectiveness of family-based cognitive behavioral therapy to family-based relaxation therapy in treating young children with obsessive-compulsive disorder. Ages 5-8. Locations in Durham, NC; Philadelphia, PA; Providence, RI.
- Effectiveness of Treatment for Relational Aggression in Urban African American Girls.
Interventional study. This study will evaluate the effectiveness of a school-based social cognitive group treatment in reducing aggression (bullying) among relationally aggressive urban African American girls. Location in Philadelphia, PA.
- Comparison of Two Psychosocial Therapies for Treating Children With Oppositional-Defiant Disorder.
Interventional study. This study will evaluate the effectiveness of two different psychosocial therapies, parent management training and collaborative problem solving, in treating children with oppositional-defiant disorder. Ages 8-12. Location in Blacksburg, VA.
- Abuse-Focused Cognitive Behavioral Therapy for Children Who Have Been Physically Abused.
Interventional study. This study will determine the effectiveness of abuse-focused cognitive behavioral therapy that is provided by a community health clinic in addressing the behavioral and emotional health needs of children and adolescents whose parents have used physical disciplinary action. Ages 5-15. Location in Pittsburgh, PA.
- A Parent-Based Intervention to Reduce Sexual Risk Behavior in Adolescents.
Interventional study. This study will evaluate the effectiveness of a parent-based intervention in reducing sexual risk behavior in high-risk Latino and African-American adolescents. Ages 11-14. Location in New York, NY.
- Peer Support for Increasing Physical Activity in People With Serious Mental Illnesses.
Interventional study. This study will determine the effectiveness of a peer support system in increasing physical activity and effecting health behavior change in people with serious mental illnesses. Ages 18-70. Location in Baltimore, MD.
- Follow-up Evaluation of Home Nurse Visitation Program for Socially Disadvantaged Women and Their Children.
Interventional study. This study will evaluate the long-term effects of a prenatal and early childhood home nurse visitation program for socially disadvantaged women and their children. Location in Elmira, NY.
- Internet-Based Treatment for Children With Traumatic Brain Injuries & Their Families: Counselor Assisted Problem Solving.
Interventional study. This study will evaluate the effectiveness of an Internet-based psychosocial treatment in improving problem-solving, communication skills, stress management strategies, and coping among children who have had a traumatic brain injury and their families. Ages 12-16. Locations in Cincinnati, OH; Cleveland, OH.
- Multi-Family Group Therapy for Reducing Behavioral Difficulties in Youth.
Interventional study. This study will examine the effectiveness of a multiple family group mental health service delivery strategy in improving mental health service use and outcome for urban, low income children of color. Ages 7 and over. Location in New York, NY.
- Integrated Treatment Program for Hypochondriasis in Primary Care Settings.
Interventional study. This study will evaluate the effectiveness of an integrated three-part treatment program in improving the quality of care and treatment outcomes of people with hypochondriasis in primary care settings. Ages 18-70. Locations in Boston, MA; Cambridge, MA.
- Promoting Infant Mental Health in Foster Care.
Interventional study. This study will evaluate the effectiveness of the Promoting First Relationships (PFR) program versus an Early Education Support (EES) program in promoting infant well-being, preventing emotional and behavioral problems, countering developmental delay, and reducing placement instability in young foster care children. Ages 10 Months-20 Months. Location in Seattle, WA.
- Comparing Cognitive Behavioral Therapy, Antidepressant Medication, and Combined Treatment in Individuals With Hypochondriasis.
Interventional study. This study will compare the effectiveness of cognitive behavioral therapy, antidepressant medication, and a combination of the two for treating hypochondriasis. Ages 21 and over. Locations in Boston, MA; New York City, NY.
- Safety and Effectiveness of Taking Choline Supplements During Pregnancy for Improving Infant Brain Development.
Interventional study. This study will evaluate the safety and effectiveness of taking choline supplements during pregnancy, and whether choline supplementation has an effect on infant development. Ages 18-45. Location in Denver, CO.
- Effectiveness of the Screen, Test, Immunize, Reduce Risk, and Refer (STIRR) Intervention for People With Both a Mental and Substance Abuse Disorder.
Interventional study. This study will determine the effectiveness of the STIRR (Screen, Test, Immunize, Reduce risk, and Refer) intervention in increasing rates of testing, immunization, referral, and treatment for blood-borne diseases, such as hepatitis and HIV, in people with both a mental disorder and a substance abuse disorder. Ages 18-65. Location in Baltimore, MD.
- Evaluation of Person-Centered Care With and Without Community Integration for Treating Psychosis in Adults of Hispanic and African Descent.
Interventional study. This study will compare standard individualized care to person-centered care and community-integrating care for treating psychosis in adults of Hispanic or African descent. Ages 18 and over. Location in New Haven, CT.
- Effectiveness of Behavior Therapy and Psychosocial Therapy for the Treatment of Tourette Syndrome and Chronic Tic Disorder.
Interventional study. This study will compare the effectiveness of supportive therapy versus habit-reversal therapy for the treatment of Tourette syndrome and chronic tic disorder. Ages 16 and over. Locations in New Haven, CT; Boston, MA; San Antonio, TX.
- A Comparison of Fluoxetine and Divalproex for the Treatment of Intermittent Explosive Disorder.
Interventional study. This study will compare the medications fluoxetine (Prozac®) and divalproex (Depakote®) for the treatment of aggressive behavior in individuals with Intermittent Explosive Disorder (IED). Ages 21-55. Location in Chicago, IL.
