Treatment for Adolescents with Depression Study (TADS)

The NIMH-funded Treatment for Adolescents with Depression Study (TADS) is a multi-site clinical research study examining the short- and long-term effectiveness of an antidepressant medication and psychotherapy alone and in combination for treating depression in adolescents ages 12 to 17. This page provides information about the study.

Questions and Answers

• Questions and Answers about TADS

News about TADS

• Science Update (November 18, 2009): Long-term Depression Treatment Leads to Sustained Recovery for Most Teens
• Science Update (May 29, 2009): Searching for Risk Factors of Suicidal Events During Antidepressant Treatment
• Science Update (Jan 15, 2009): Adolescents with Depression Not Harmed in Studies Using Placebo
• Science Update (April 8, 2008): Maintenance Treatment Crucial for Teens' Recovery from Depression
• Press Release (October 1, 2007): Depressed Adolescents Respond Best to Combination Treatment
• Press Release (Aug 17, 2004): Combination Treatment Most Effective in Adolescents with Depression

Related Information

• Child and Adolescent Mental Health
• Depression in Children and Adolescents
• Depression
• Antidepressant Medications for Children and Adolescents: Information for Parents and Caregivers
• Clinical trial information about the Treatment for Adolescents with Depression Study (TADS) from ClinicalTrials.gov 
• Limited Access Dataset from TADS

Surgeon General Reports

• “Children and Mental Health”  — Chapter Three from Mental Health: Report of the Surgeon General
• Report of the Surgeon General’s Conference on Children's Mental Health: A National Action Agenda